Frailty, multimorbidity patterns and mortality in institutionalized older adults in Italy.

ABSTRACT:

Background

Little is known on how frailty influences clinical outcomes in persons with specific multimorbidity patterns.

Aims

To investigate the interplay between multimorbidity and frailty in the association with mortality in older individuals living in nursing homes (NH).

Methods

We considered 4,131 NH residents aged 60 years and over, assessed through the interRAI LTCF instrument between 2014 and 2018. Follow-up was until 2019. Considering four multimorbidity patterns identified via principal component analysis, subjects were stratified in tertiles (T) with respect to their loading values. Frailty Index (FI) considered 23 variables and a cut-off of 0.24 distinguished between high and low frailty levels. For each pattern, all possible combinations of tertiles and FI

SUBMITTER: Damiano C 

PROVIDER: S-EPMC9562060 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature