Management of tuberculosis infection in Victorian children: A retrospective clinical audit of factors affecting treatment completion.

ABSTRACT:

Background

Tuberculosis preventive treatment (TPT) is strongly recommended for children following infection with Mycobacterium tuberculosis because of their high risk of progression to active tuberculosis, including severe disseminated disease. We describe the implementation of TPT for children and adolescents with evidence of tuberculosis infection (TBI) at Victoria's largest children's hospital and examine factors affecting treatment completion.

Methods

We conducted a retrospective clinical audit of all children and adolescents aged <18 years diagnosed with latent TBI at the Royal Children's Hospital, Melbourne, between 2010 and 2016 inclusive. The primary outcome was treatment completion, defined as completing TPT to within one month of a target duration for the specified

SUBMITTER: Holmes RH 

PROVIDER: S-EPMC9562148 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature