A Simple, Efficient, Eco-Friendly Sample Preparation Procedure for the Simultaneous Determination of Hormones in Meat and Fish Products by Gas Chromatography-Mass Spectrometry.

ABSTRACT: Food safety can be severely compromised by the presence of chemical contaminants. This has raised a pressing need to develop efficient analytical methods for their determination at very low levels in complex food matrices. In this manuscript, we developed a simple, sensitive, fast, green analytical method for the determination of thirteen natural and synthetic hormones from different families including progestogens, estrogens and androgens in meat and fish products. The method involves direct extraction with a (9:1) acetonitrile-water mixture and subsequent purification of the extract by semi-automated solid-phase extraction on a sorbent column (hydrophilic-lipophilic copolymer of N-vinylpyrrolidone and divinylbenzene). This treatment enriches samples with the target compounds while removi

SUBMITTER: Chafi S 

PROVIDER: S-EPMC9562678 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature