Insulin secretion and action with increasing age - A comparison between Middle Eastern immigrants and native Swedes.

ABSTRACT:

Aims

Little is known how insulin secretion and action change over time in populations of different ethnicities. We studied changes in insulin secretion and action with increasing age in Iraqi-born immigrants and native Swedes, and investigated if the changes were modified by region of origin.

Methods

Residents of Malmö, 30-75 years of age born in Iraq or Sweden, were invited to participate in this population-based, cross-sectional study. Health examination, medical history, lifestyle, sociodemographic data, and fasting blood samples were assessed. Oral glucose tolerance tests were performed and insulin secretion (disposition index, DIo) and insulin sensitivity index (ISI) calculated using the Matsuda indices.

Results

In total 1881 people participated; 1193 Iraqi- and

SUBMITTER: Dhaher NF 

PROVIDER: S-EPMC9563179 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature