Missed anti-D immune globulin administration to postpartum patients in 2 health systems: an unrecognized patient safety risk

ABSTRACT:

BACKGROUND

Maternal-fetal Rh-alloimmunization is a rare but potentially fatal event, most often caused by maternal exposure to D-antigen-presenting Rh-positive erythrocytes at the time of delivery. Prophylaxis with anti-D immune globulin is highly effective with a low side-effect profile and results in a dramatically decreased risk of alloimmunization. Postpartum anti-D immune globulin prophylaxis is recommended by national societies to reduce Rh-alloimmunization. We hypothesized that a small number of postpartum patients do not receive prophylaxis as indicated.  

OBJECTIVE

We investigated patients in 2 separate health systems that did not receive indicated prophylaxis and devised a suite of Electronic Health Record interventions to prevent future errors.

STUDY DESIGN

SUBMITTER: Brackney K 

PROVIDER: S-EPMC9563491 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature