Paracetamol preceding very preterm birth: Is it safe?

ABSTRACT:

Introduction

The use of paracetamol for pain relief in pregnancy is common. However, the influence of paracetamol on the perinatal adaptation of high-risk infants has not been studied. These data are important for safety, since another inhibitor of prostaglandin synthesis is harmful to infants born very preterm and increases serious morbidity. We studied whether the use of paracetamol had an adverse influence on neonatal adaptation and the outcomes of infants during the first hospitalization.

Material and methods

We studied the patient records of high-risk mothers and their infants born before 32 weeks of gestation for multiple variables over a period of 84 months in Oulu University Hospital, a regional tertiary care hospital caring for high-risk deliveries and providing neo

SUBMITTER: Laitala A 

PROVIDER: S-EPMC9564685 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature