Residual tumor and primary debulking surgery vs interval debulking surgery in stage IV epithelial ovarian cancer.

ABSTRACT:

Introduction

It is debated whether women with FIGO (International Federation of Gynecology and Obstetrics) Stage IV epithelial ovarian cancer should be offered primary debulking surgery (PDS) or interval debulking surgery (IDS). Furthermore, the impact of complete resection of intra-abdominal disease (R0) despite their extra-abdominal metastases is questioned. The objective of this study was to investigate the impact of intra-abdominal residual tumor, Stage IVA vs IVB, the localization and number of metastases defining Stage IV disease on overall survival (OS) comparing PDS and IDS in FIGO Stage IV epithelial ovarian cancer.

Material and methods

We included 2091 women registered with Stage IIIC-IV ovarian cancer in the Danish Gynecological Cancer Database during 2009-2016. T

SUBMITTER: Sorensen SM 

PROVIDER: S-EPMC9564730 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature