Systemic hormonal contraception and risk of venous thromboembolism.

ABSTRACT:

Introduction

The increased risk of venous thromboembolism associated with the use of hormonal contraception is well recognized, but evidence regarding hormonal contraception containing natural estradiol is limited. This study aimed to assess the associations between the patterns of use of different systemic hormonal contraceptives and the risk of venous thromboembolism during 2017-2019.

Material and methods

All fertile-aged women (15-49 years) living in Finland in 2017 and using hormonal contraception in 2017 and their 1:1 age- and residence-matched controls not using hormonal contraception in 2017 (altogether 587 559 women) were selected from the Prescription Centre. All incident venous thromboembolism cases during 2018-2019 and their 4:1 age-matched controls were further a

SUBMITTER: Heikinheimo O 

PROVIDER: S-EPMC9564731 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature