Understanding the immunological landscape of England during SARS-CoV2 Omicron variant wave.

ABSTRACT: Understanding the scale of the threat posed by SARS-CoV2 B.1.1.529, or Omicron, variant formed a key problem in public health in the early part of 2022. Early evidence indicated that the variant was more transmissible and less severe than previous variants. As the virus was expected to spread quickly through the population of England, it was important that some understanding of the immunological landscape of the country was developed. This paper attempts to estimate the number of people with good immunity to the Omicron variant, defined as either recent infection with two doses of vaccine, or two doses of vaccine with a recent booster dose. To achieve this, we use a process of iterative proportional fitting to estimate the cell values of a contingency table, using national immunisation rec

SUBMITTER: Shingleton J 

PROVIDER: S-EPMC9565446 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature