Thermal and Medium Stability Study of Polyvidone-Modified Graphene Oxide-Coated Gold Nanorods with High Photothermal Efficiency.

ABSTRACT: Coating gold nanorods (AuNRs) with different materials, such as polymers and graphene-based materials, has improved their biocompatibility. However, these materials have been shown to cause the instability of AuNRs in thermal and culture mediums. In addressing this issue, we herein report the synthesis, thermal and culture medium stability, and photothermal profiling of Polyvidone (PVP)-modified graphene oxide (GO)-coated AuNRs (mGO@AuNRs). The AuNRs, with a size of 40.70 nm × 9.16 nm and absorbing at 820 nm, were coated with PVP, GO, and mGO. The colloidal stability of the nanocomposites was tested in three commonly used cell culture mediums: the Roswell Park Memorial Institute 1640 (RPMI-1640), Dulbecco's Modified Eagle Medium, (DMEM) and Dulbecco's phosphate-buffered saline (PBS) using

SUBMITTER: Lebepe TC 

PROVIDER: S-EPMC9565574 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature