Reliability and feasibility of visual grading systems and quantitative indexes on [^99mTc]Tc-DPD imaging for cardiac amyloidosis.

ABSTRACT: We aimed to evaluate the reliability and feasibility of visual grading systems and various quantitative indexes of [^99mTc]Tc-DPD imaging for cardiac amyloidosis (CA). Patients who underwent [^99mTc]Tc-DPD imaging with suspicion of CA were enrolled. On the planar image, myocardial uptake was visually graded using Perugini's and Dorbala's methods (PS and DS). As [^99mTc]Tc-DPD indexes, heart-to-whole body ratio (H/WB) and heart-to-contralateral lung ratio (H/CL) were measured on planar image. SUVmax, SUVmean, total myocardial uptake (TMU), and C-index were measured on SPECT/CT. Inter-observer agreement of the indexes and their association with visual grading and clinical factors were evaluated. A total of 152 [^99mTc]Tc-DPD images, of which 18 were po

SUBMITTER: Bae S 

PROVIDER: S-EPMC9568548 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature