Regional lymph node metastasis detected on preoperative CT and/or FDG-PET may predict early recurrence of pancreatic adenocarcinoma after curative resection.

ABSTRACT: The objective of this study was to evaluate the role of regional lymph node (LN) metastasis detected on preoperative CT and/or ¹⁸F-fluoro-2-deoxyglucose-positron emission tomography (FDG-PET) scans in the prediction of early tumor recurrence after curative surgical resection of pancreatic ductal adenocarcinoma (PDAC). This retrospective study included 137 patients who underwent upfront surgery with R0 resection of PDAC between 2013 and 2016. Regional LN metastasis was identified using two criteria: positive findings for regional LN metastasis on either preoperative CT or FDG-PET scans (LN_OR), or on both preoperative CT and FDG-PET scans (LN_AND). A total of 55 patients had early tumor recurrence within 12 months after curative resection. Univariable and mult

SUBMITTER: Yoon JK 

PROVIDER: S-EPMC9568602 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature