Self-collected versus medic-collected sampling for human papillomavirus testing among women in Lagos, Nigeria: a comparative study.

ABSTRACT:

Objective

To evaluate the feasibility and performance of self-collected vaginal swab samples for HPV screening among women in Lagos, Nigeria.

Methods

A cross-sectional study was implemented from March to August 2020 among sexually active women. Study participants provided same-day paired vaginal swab samples. Medic-sampling and poster-directed self-sampling methods were used to collect the two samples per participant. A real-time PCR assay detected HPV 16, HPV 18, other-high-risk (OHR) HPV, and the human β-globin gene. The self-collected samples' sensitivity, specificity, and accuracy were determined against the medic-collected samples using the MedCalc Online Diagnostic Calculator.

Results

Of the 213 women aged 16 ~ 63-year-old recruited, 187 (88%) participants had c

SUBMITTER: Feng N 

PROVIDER: S-EPMC9569041 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature