Do Circulating Redox Biomarkers Have Diagnostic Significance in Alcohol-Intoxicated People?

ABSTRACT: The toxic properties of ethanol are inextricably linked to oxidative stress. Despite many reports on the effects of alcohol dependence on blood redox homeostasis, there are no data on the oxidative stress profile in alcohol-poisoned cases. There are also no data on the diagnostic usefulness of redox biomarkers determined post-mortem in various biological fluids. This work investigates the utility of enzymatic and non-enzymatic antioxidant barrier, redox status, and oxidative/nitrosative stress biomarkers in different biological fluids (such as blood, urine, vitreous humor, and cerebrospinal fluid) in the post-mortem study of patients with acute alcohol intoxication. The study group included those who died due to acute ethanol intoxication (n = 22). The research showed a significant

SUBMITTER: Maciejczyk M 

PROVIDER: S-EPMC9569923 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature