CPlot: Contig-Plotting Visualization for the Analysis of Short-Read Nucleotide Sequence Alignments.

ABSTRACT: Advances in the next-generation sequencing technology have led to a dramatic decrease in read-generation cost and an increase in read output. Reconstruction of short DNA sequence reads generated by next-generation sequencing requires a read alignment method that reconstructs a reference genome. In addition, it is essential to analyze the results of read alignments for a biologically meaningful inference. However, read alignment from vast amounts of genomic data from various organisms is challenging in that it involves repeated automatic and manual analysis steps. We, here, devised cPlot software for read alignment of nucleotide sequences, with automated read alignment and position analysis, which allows visual assessment of the analysis results by the user. cPlot compares sequence similari

SUBMITTER: Ji M 

PROVIDER: S-EPMC9570162 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature