Photochemical Consideration in the Interactions between Blood Proteins and Layered Inorganic Materials.

ABSTRACT: Interactions between layered double hydroxide (LDH) nanomaterials and plasma proteins according to their particle size and surface charge were evaluated. The LDHs with different particle size (150, 350 and 2000 nm) were prepared by adjusting hydrothermal treatment and urea hydrolysis and subsequent organic coating with citrate, malite and serite was applied to control the surface charge (ζ-potential: -15, 6 and 36 mV). Adsorption isotherms and Stern-Volmer plots for fluorescence quenching indicated that the human blood plasma had weak interactions toward all the types of LDHs. The adsorption isotherms did not show significant differences in the size and surface charges, while the fluorescence quenching ratio increased with the increase in the surface charge, implying that electrostatic int

SUBMITTER: Yamaguchi T 

PROVIDER: S-EPMC9570392 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature