Ontology highlight
ABSTRACT:
SUBMITTER: Maneenet J
PROVIDER: S-EPMC9570665 | biostudies-literature | 2022 Sep
REPOSITORIES: biostudies-literature
Maneenet Juthamart J Tawila Ahmed M AM Omar Ashraf M AM Phan Nguyen Duy ND Ojima Chiharu C Kuroda Masahiro M Sato Mao M Mizoguchi Mio M Takahashi Ikue I Awale Suresh S
Plants (Basel, Switzerland) 20220921 19
An n-hexane extract of <i>Callistemon subulatus</i> was found to exhibit potent cytotoxicity against PANC-1 human pancreatic cancer cells, preferentially under nutrition starvation conditions, with a PC<sub>50</sub> value of 6.2 µg/mL. Phytochemical investigation of this bioactive extract resulted in the isolation of fifteen compounds (<b>1</b>-<b>15</b>), including a new compound, subulatone A (-). The structure of compound <b>1</b> was elucidated using HRFABMS and NMR spectroscopic analyses. T ...[more]