Microvascular complications identify a specific coronary atherosclerotic phenotype in patients with type 2 diabetes mellitus.

ABSTRACT:

Background

Patients with type 2 diabetes mellitus (T2DM) are considered as a homogeneous cohort of patients. However, the specific role of diabetic microvascular complications (DMC), in determining the features of coronary plaques is poorly known. We investigated whether the presence of DMC may identify a different phenotype of patients associated to specific clinical, angiographic, optical coherence tomography (OCT) features and different prognosis.

Methods

We prospectively enrolled consecutive T2DM patients with obstructive coronary artery disease (CAD) at their first coronary event. Patients were stratified according to the presence or absence of DMC, including diabetic retinopathy, diabetic neuropathy, and diabetic nephropathy. OCT assessment of the culprit vessel was pe

SUBMITTER: Montone RA 

PROVIDER: S-EPMC9571474 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature