Holistic Integration of Omics Tools for Precision Nutrition in Health and Disease.

ABSTRACT: The combination of multiple omics approaches has emerged as an innovative holistic scope to provide a more comprehensive view of the molecular and physiological events underlying human diseases (including obesity, dyslipidemias, fatty liver, insulin resistance, and inflammation), as well as for elucidating unique and specific metabolic phenotypes. These omics technologies include genomics (polymorphisms and other structural genetic variants), epigenomics (DNA methylation, histone modifications, long non-coding RNA, telomere length), metagenomics (gut microbiota composition, enterotypes), transcriptomics (RNA expression patterns), proteomics (protein quantities), and metabolomics (metabolite profiles), as well as interactions with dietary/nutritional factors. Although more evidence is still

SUBMITTER: Ramos-Lopez O 

PROVIDER: S-EPMC9572439 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature