In Silico Evaluation of Natural Flavonoids as a Potential Inhibitor of Coronavirus Disease.

ABSTRACT: The recent coronavirus disease (COVID-19) outbreak in Wuhan, China, has led to millions of infections and the death of approximately one million people. No targeted therapeutics are currently available, and only a few efficient treatment options are accessible. Many researchers are investigating active compounds from natural plant sources that may inhibit COVID-19 proliferation. Flavonoids are generally present in our diet, as well as traditional medicines and are effective against various diseases. Thus, here, we reviewed the potential of flavonoids against crucial proteins involved in the coronavirus infectious cycle. The fundamentals of coronaviruses, the structures of SARS-CoV-2, and the mechanism of its entry into the host's body have also been discussed. In silico studies have been s

SUBMITTER: Kashyap P 

PROVIDER: S-EPMC9572657 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature