Supplementation with Queen Bee Larva Powder Extended the Longevity of Caenorhabditis elegans.

ABSTRACT: Queen bee larva (QBL) is one kind of important edible insect that is harvested during royal jelly production process. QBL has many physiological functions; however, limited information is available regarding its antiaging effects. In this study, the antiaging function of freeze-dried QBL powder (QBLP) was investigated by combining the Caenorhabditis elegans (C. elegans) model and transcriptomics. The administration of QBLP to C. elegans was shown to improve lifespan parameters. Additionally, QBLP improved the mobility of nematodes. Transcriptome analysis showed the differentially expressed genes (DEGs) were significantly enriched in Gene Ontology (GO) terms that were almost all related to the biological functions of cell metabolism and stress, which are associated with

SUBMITTER: Zhao T 

PROVIDER: S-EPMC9573043 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature