Switching Antipsychotic Medications in People with Schizophrenia: A 4-Year Naturalistic Study.

ABSTRACT: Although generally effective in ameliorating the core manifestations of schizophrenia, antipsychotics (APs) may lead to only suboptimal responses or may be associated with a variety of treatment-related adverse events which require additional treatment strategies. Under such clinical circumstances, switching APs represents a rational treatment option. The present study aimed to identify the variables that predict AP switch and to quantify the frequency of this phenomenon in people with schizophrenia in real-life. A secondary analysis was conducted on the data collected at baseline and at a 4-year follow-up from a large sample of community-dwelling Italian people with schizophrenia. Demographic and clinical variables as well as information about AP treatment were recorded at two time points

SUBMITTER: Cascino G 

PROVIDER: S-EPMC9573332 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature