Pyrethroid Resistance Situation across Different Eco-Epidemiological Settings in Cameroon.

ABSTRACT: Rapid emergence and spread of pyrethroid resistance in Anopheles gambiae populations is among the main factors affecting malaria vector control in Cameroon, but there is still not enough data on the exact pyrethroid resistance status across Cameroon. The present study assessed pyrethroid resistance profile in different eco-epidemiological settings in Cameroon. Susceptibility bioassay tests were performed with F0 An. gambiae females aged three to five days. Mosquito susceptibility to both permethrin and deltamethrin was assessed. Species of the An. gambiae s.l. complex were identified using molecular diagnostic tools. Target site mutations conferring resistance were detected using Taqman assays. Quantitative reverse transcription-real-time PCR (qRT-PCR) 3-plex TaqMan

SUBMITTER: Kala-Chouakeu NA 

PROVIDER: S-EPMC9573433 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature