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Association of Urinary Iodine Concentration with Depressive Symptoms among Adults: NHANES 2007-2018.


ABSTRACT: The association between iodine status and depressive symptoms has not been investigated in the general population. Therefore, we drew 8935 participants from the National Health and Nutrition Examination Survey (NHANES) 2007-2018 to explore their association. In NHANES, Inductively Coupled Plasma Dynamic Reaction Cell Mass Spectroscopy was utilized to measure urinary iodine concentration (UIC), and Patient Health Questionnaire-9 was used to assess depressive symptoms. Meanwhile, we fitted logistic regression and restricted cubic spline models. We found that high UIC was associated with a higher prevalence of depressive symptoms than the normal UIC group (OR: 1.50, 95% CI: 1.04-2.16). This association was particularly pronounced and further strengthened among females (OR: 1.90, 95% CI: 1.19-

SUBMITTER: Chen S 

PROVIDER: S-EPMC9573473 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature