A taxonomy of the brain's white matter: twenty-one major tracts for the 21st century.

ABSTRACT: The functional and computational properties of brain areas are determined, in large part, by their connectivity profiles. Advances in neuroimaging and network neuroscience allow us to characterize the human brain noninvasively, but a comprehensive understanding of the human brain demands an account of the anatomy of brain connections. Long-range anatomical connections are instantiated by white matter, which itself is organized into tracts. These tracts are often disrupted by central nervous system disorders, and they can be targeted by neuromodulatory interventions, such as deep brain stimulation. Here, we characterized the connections, morphology, traversal, and functions of the major white matter tracts in the brain. There are major discrepancies across different accounts of white matter

SUBMITTER: Bullock DN 

PROVIDER: S-EPMC9574243 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature