Impact of prior bariatric surgery on risk and severity of COVID-19 infection: A meta-analysis of observational studies.

ABSTRACT:

Background

The association of prior bariatric surgery (BS) with infection rate and prognosis of coronavirus disease 2019 (COVID-19) remains unclear. We conducted a meta-analysis of observational studies to address this issue.

Methods

We searched databases including MEDLINE, Embase, and CENTRAL from inception to May, 2022. The primary outcome was risk of mortality, while secondary outcomes included risk of hospital/intensive care unit (ICU) admission, mechanical ventilation, acute kidney injury (AKI), and infection rate.

Results

Eleven studies involving 151,475 patients were analyzed. Meta-analysis showed lower risks of mortality [odd ratio (OR)= 0.42, 95% CI: 0.27-0.65, p < 0.001, I² = 67%; nine studies; 151,113 patients, certainty of evidence (COE):moderat

SUBMITTER: Hung KC 

PROVIDER: S-EPMC9574468 | biostudies-literature | 2022 Nov-Dec

REPOSITORIES: biostudies-literature