Value of ¹⁸F FDG-PET/CT parameters on long term follow-up for patients with non-small cell lung cancer.

ABSTRACT:

Objectives

The purpose of this study was to investigate the value of PET/CT in the preoperative staging of non-small cell lung cancer in predicting long-term survival and diagnostic performance, validated by histopathology following surgical resection.

Methods

Between 02/2009 and 08/2011, 255 patients with non-small cell lung cancer were included in this single-center prospective study. All underwent 18F FDG-PET/CT for pre-operative staging, and in 243 patients complete surgical resection was possible. Regarding lymph node involvement and extrathoracic metastases, sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) were calculated using the histopathological staging as reference. Median follow-up for censored patients was 9.1 years.

SUBMITTER: Zoair M 

PROVIDER: S-EPMC9574653 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature