Effect of early metoprolol before PCI in ST-segment elevation myocardial infarction on infarct size and left ventricular ejection fraction. A systematic review and meta-analysis of clinical trials.

ABSTRACT:

Aim

This meta-analysis aims to look at the impact of early intravenous Metoprolol in ST-segment elevation myocardial infarction (STEMI) before percutaneous coronary intervention (PCI) on infarct size, as measured by cardio magnetic resonance (CMR) and left ventricular ejection fraction.

Methods

We searched the following databases: PubMed, Scopus, Cochrane library, and Web of Science. We included only randomized control trials that reported the use of early intravenous Metoprolol in STEMI before PCI on infarct size, as measured by CMR and left ventricular ejection fraction. RevMan software 5.4 was used for performing the analysis.

Results

Following a literature search, 340 publications were found. Finally, 18 studies were included for the systematic review, and 8 clini

SUBMITTER: Motawea KR 

PROVIDER: S-EPMC9574721 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature