Association between early life famine exposure and risk of metabolic syndrome in later life.

ABSTRACT:

Background

Previous studies reported that famine exposure had an effect on metabolic syndrome (MetS). However, there is an inadequacy of study regarding the association between famine exposure, adulthood general obesity, and the risk of MetS.

Methods

A total of 8883 subjects aged ≥40 years from Jiading community in Shanghai were included. We defined famine exposure subgroups as nonexposed (1963-1974), fetal exposed (1959-1962), childhood exposed (1949-1958), and adolescence exposed (1941-1948). MetS was defined based on the National Cholesterol Education Program Adult Treatment Panel III (NCEP-ATP III) criteria.

Results

Compared with the nonexposed group, the risks of MetS were increased in the fetal-, childhood-, and adolescence-exposed groups with odds ratios (OR) a

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC9574738 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature