Efficacy of a formulation of sarolaner/moxidectin/pyrantel (Simparica Trio^®) for the prevention of Thelazia callipaeda canine eyeworm infection.

ABSTRACT:

Background

For a long time known as the oriental eyeworm, Thelazia callipaeda is a zoonotic nematode that infects the eyes of a wide range of vertebrate hosts including dogs, cats, wildlife carnivores, lagomorphs, and humans. The high occurrence of this infection in Europe and the first cases in the United States have increased scientific interest in the parasite, as it also represents a risk for people living in endemic areas. Therefore, treatment and prevention of thelaziosis in canine population are advocated to reduce the risk of human infection as well. Here, we assessed the efficacy of a formulation containing sarolaner/moxidectin/pyrantel (Simparica Trio^®) administered orally at monthly intervals, for the prevention of establishment of infection with T. callipaeda

SUBMITTER: Bezerra-Santos MA 

PROVIDER: S-EPMC9575252 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature