Self-perceived burden predicts lower quality of life in advanced cancer patients: the mediating role of existential distress and anxiety

ABSTRACT:

Background

Self-perceived burden (SPB) is an important predictor of quality of life (QoL) in patients with advanced cancer. However, the mechanism how SPB affects patients’ QoL remains unclear. This study aimed to examine the potential mediating roles of existential distress (ED) and anxiety in the relationship between SPB and QoL.

Methods

A multicenter cross-sectional study was conducted. 352 advanced cancer patients were recruited from three hospitals in southeast of China. The Self-perceived Burden Scale, the Existential Distress Scale, the Hospital Anxiety and Depression Scale, and the Quality-of-Life Concerns in the End of Life Questionnaire were adopted to collect data. Hayes’s bootstrapping method was used to analyze the data.

Results

SPB was negatively as

SUBMITTER: Xiaodan L 

PROVIDER: S-EPMC9575302 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature