Outcomes of pediatric acute myeloid leukemia treatment in Western Kenya.

ABSTRACT:

Background

Pediatric acute myeloid leukemia (AML) is a challenging disease to treat in low- and middle-income countries (LMICs). Literature suggests that survival in LMICs is poorer compared with survival in high-income countries (HICs).

Aims

This study evaluates the outcomes of Kenyan children with AML and the impact of sociodemographic and clinical characteristics on outcome.

Methods and results

A retrospective medical records study was performed at Moi Teaching and Referral Hospital (MTRH) in Eldoret, Kenya, between January 2010 and December 2018. Sociodemographic and clinical characteristics, and treatment outcomes were evaluated. Chemotherapy included two "3 + 7" induction courses with doxorubicin and cytarabine and two "3 + 5" consolidation courses with etoposid

SUBMITTER: van Weelderen RE 

PROVIDER: S-EPMC9575503 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature