Understanding the association between adverse childhood experiences and subsequent attention deficit hyperactivity disorder: A systematic review and meta-analysis of observational studies.

ABSTRACT:

Objectives

Attention deficit hyperactivity disorder (ADHD) is a common neurodevelopmental disorder in childhood, which may be related to adverse childhood experiences (ACEs). Our study aims to explore the association between ACEs and subsequent ADHD, and analyze the potential moderators.

Methods

Literature search was conducted by a combined computer-assisted and manual method. Studies were included if they had reported the association between ACEs and subsequent ADHD. Overall estimates of odds ratios (ORs) were obtained using random-effects meta-analyses, meta-regressions and further stratified analyses were conducted to examine potential moderator variables.

Results

Totals of 70 studies involving nearly 4 million participants from among 6,452 unique articles were inc

SUBMITTER: Zhang N 

PROVIDER: S-EPMC9575611 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature