Impact on clinical outcomes from transcatheter closure of the Fontan fenestration: A systematic review and meta-analysis.

ABSTRACT:

Background

Meta-analysis of the impact on clinical outcome from transcatheter closure of Fontan fenestration.

Methods

Cochrane, Embase, MEDLINE, and Open-Gray were searched. Parameters such as changes in oxygen saturation, cavo-pulmonary pressure, maximum heart rate during exercise, exercise duration, and oxygen saturation after fenestration closure were pooled and statistical analysis performed.

Results

Among 922 publications, 12 retrospective observational studies were included. The included studies involved 610 patients, of which 552 patients (90.5%) had a fenestration. Of those patients, 505 patients (91.5%) underwent attempt at trans-catheter closure. When it could be estimated, the pooled overall mean age at trans-catheter fenestration closure was 6.6 ± 7.4 year

SUBMITTER: Greenleaf CE 

PROVIDER: S-EPMC9576841 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature