Early identification of delayed extubation following cardiac surgery: Development and validation of a risk prediction model.

ABSTRACT:

Background

Successful weaning and extubation after cardiac surgery is an important step of postoperative recovery. Delayed extubation is associated with poor prognosis and high mortality, thereby contributing to a substantial economic burden. The aim of this study was to develop and validate a prediction model estimate the risk of delayed extubation after cardiac surgery based on perioperative risk factors.

Methods

We performed a retrospective cohort study of adult patients undergoing cardiac surgery from 2014 to 2019. Eligible participants were randomly assigned into the development and validation cohorts, with a ratio of 7:3. Variables were selected using least absolute shrinkage and selection operator (LASSO) logistic regression model with 10-fold cross-validation. Multiv

SUBMITTER: Li X 

PROVIDER: S-EPMC9576842 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature