Considerations into pharmacogenomics of COVID-19 pharmacotherapy: Hope, hype and reality.

ABSTRACT: COVID-19 medicines, such as molnupiravir are beginning to emerge for public health and clinical practice. On the other hand, drugs display marked variability in their efficacy and safety. Hence, COVID-19 medicines, as with all drugs, will be subject to the age-old maxim "one size prescription does not fit all". In this context, pharmacogenomics is the study of genome-by-drug interactions and offers insights on mechanisms of patient-to-patient and between-population variations in drug efficacy and safety. Pharmacogenomics information is crucial to tailoring the patients' prescriptions to achieve COVID-19 preventive and therapeutic interventions that take into account the host biology, patients' genome, and variable environmental exposures that collectively influence drug efficacy and safety

SUBMITTER: Al-Taie A 

PROVIDER: S-EPMC9576910 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature