Pediatric reference interval verification for common biochemical assays on the Abbott Alinity system.

ABSTRACT:

Objectives

The quality of clinical laboratory service depends on quality laboratory operations and accurate test result interpretation based on reference intervals (RIs). As new analytical systems continue to be developed and improved, previously established RIs must be verified. The Canadian Laboratory Initiative on Pediatric Reference Intervals (CALIPER) has established comprehensive RIs for many biomarkers on several analytical systems. Here, published CALIPER RIs for 28 chemistry assays on the Abbott ARCHITECT were assessed for verification on the newer Alinity system.

Methods

An analytical validation was first completed to assess assay performance. CALIPER serum samples (100) were analyzed for 28 chemistry assays on the Alinity system. The percentage of results falling

SUBMITTER: Bohn MK 

PROVIDER: S-EPMC9577062 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature