Twice daily low frequency rTMS for treatment-resistant auditory hallucinations.

ABSTRACT:

Background

Repetitive transcranial magnetic stimulation (rTMS) has emerged as a therapeutic solution in patients with treatment-resistant auditory verbal hallucinations. However, the optimal stimulation parameters remain unclear, especially for patients with clozapine-resistant symptoms.

Method

In an open label retrospective study, we investigated whether parameters of stimulation that were useful in patients with major depressive disorder would help schizophrenia patients with treatment-resistant auditory verbal hallucinations. Fourteen participants, including 9 under clozapine, received 30 sessions of 1 Hz rTMS over 3 weeks (360 pulses per sessions delivered with 60 s 'on' and 30 s 'off' at 110% of the resting motor threshold, 2 sessions per day). Stimulations were applied

SUBMITTER: Brunelin J 

PROVIDER: S-EPMC9577245 | biostudies-literature | 2023 Jan-Apr

REPOSITORIES: biostudies-literature