The role and mechanism of epidermal growth factor receptor in hemodynamic induction of abdominal aortic aneurysm formation.

ABSTRACT:

Background

Abdominal aortic aneurysm (AAA) is a serious threat to human health, and in the event of aneurysm rupture, the rates of disability and mortality are high. At present, the treatment of AAA mainly includes craniotomy and endovascular therapy. With advances in technology, although the safety of the treatment is improving, there is still a risk associated with surgery. Therefore, the exploration of non-invasive treatment options for aneurysms is worthwhile. The etiology of aneurysms must be investigated to identify the target of non-invasive treatment.

Methods

In the experimental group, bilateral common carotid arteries were ligated, while in the control group, bilateral common carotid arteries were exposed. After 5 days, the rabbits were sacrificed, and the hearts we

SUBMITTER: Liu L 

PROVIDER: S-EPMC9577755 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature