Establishment and validation of an individualized nomogram for survival prediction of primary mediastinal germ cell tumors based on the SEER database

ABSTRACT:

Background

Primary mediastinal germ cell tumors (PMGCT) represent a rare but sometimes highly aggressive type of mediastinal tumors. The current prognostic models for PMGCT are insufficient. This study was undertaken to establish and validate an individualized nomogram for predicting the overall survival (OS) of patients with PMGCT.

Methods

We conducted a retrospective analysis of patients with PMGCT diagnosed between 2000 and 2018 in the Surveillance, Epidemiology, and End Results (SEER) database in the United States. Clinical variables included surgery subtype, gender, treatment regimens, age, histology, tumor size, stage, chemotherapy, radiation, race, and survival-related information. The main outcome measure was survival duration. The Kaplan-Meier method along with t

SUBMITTER: Qi L 

PROVIDER: S-EPMC9577810 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature