Integrative analyses of genes related to liver ischemia reperfusion injury.

ABSTRACT:

Background

Liver ischemia reperfusion injury (LIRI) is not only a common injury during liver transplantation and major hepatic surgery, but also one of the primary factors that affect the outcome of postoperative diseases. However, there are still no reliable ways to tackle the problem. Our study aimed to find some characteristic genes associated with immune infiltration that affect LIRI, which can provide some insights for future research in the future. Therefore, it is essential for the treatment of LIRI, the elucidation of the mechanisms of LIRI, and exploring the potential biomarkers. Efficient microarray and bioinformatics analyses can promote the understanding of the molecular mechanisms of disease occurrence and development.

Method

Data from GSE151648 were downloaded

SUBMITTER: Wang HP 

PROVIDER: S-EPMC9578272 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature