Timed-averaged blood pressure showed a J-curve association with stroke in elderly chronic kidney disease patients.

ABSTRACT:

Background

The risk factors for stroke in elderly patients with chronic kidney disease (CKD) are not well understood. This study aimed to explore the influence of systolic blood pressure (SBP) on the risk of stroke in a large cohort of elderly patients with stage 3-5 CKD.

Methods

We retrospectively identified 665 patients hospitalized in Beijing Friendship Hospital from January 2000 to December 2021. Patients were followed up until the occurrence of stroke or death. Multivariate logistic regression analysis and Cox proportional hazard models were used to analyze the risk factors for stroke according to the presence or absence of CKD. The association between CKD and stroke was further evaluated regarding the role of SBP in the hypertensive population.

Results

In indivi

SUBMITTER: Fu C 

PROVIDER: S-EPMC9578479 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature