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Investigating fecal microbial transplant as a novel therapy in dogs with inflammatory bowel disease: A preliminary study.


ABSTRACT:

Background

There are limited studies investigating the use of fecal microbial transplant (FMT) in dogs with inflammatory bowel disease (IBD). The aim of this preliminary study was to assess the feasibility of adding FMT to standard therapy (corticosteroids and a hypoallergenic diet) for dogs with IBD and to and to describe the changes in measured outcomes after 30 days of treatment.

Methods

Thirteen client-owned dogs with IBD were enrolled in this double blinded, randomized clinical trial. All dogs received corticosteroid therapy and a hypoallergenic diet; dogs were randomized to receive either placebo or FMT. Measured outcomes included the canine chronic enteropathy clinical activity index (CCECAI) at 1 week and 1 month after enrolment. Fecal microbiota were analyzed after

SUBMITTER: Collier AJ 

PROVIDER: S-EPMC9578606 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature