Lung SBRT credentialing in the Canadian OCOG-LUSTRE randomized trial

ABSTRACT: Highlights • We report on the credentialing experience of a Phase III trial of SBRT versus hypofractionated RT for stage I lung cancer.• Elements included a site survey, phantom test, and a standardized case for a peripheral and central tumour.• Approximately 1/3 of plans required resubmission due to major deviations,but were not biased towards centre experience versus not.• There was contour variability demonstrated, whereas target coverage and dose constraints were largely per-protocol.• Such an exercise is important for studies that rely on high precision radiotherapy, and to ensure optimal trial quality.

Purpose

To report on the Stereotactic Body Radiation Therapy (SBRT) credentialing experience during the Phase III Ontario Clinical Oncology Group (OCOG) LUSTRE trial for stage

SUBMITTER: Swaminath A 

PROVIDER: S-EPMC9579727 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature