Genome-wide selection signatures reveal widespread synergistic effects of two different stressors in Drosophila melanogaster.

ABSTRACT: Experimental evolution combined with whole-genome sequencing (evolve and resequence (E&R)) is a powerful approach to study the adaptive architecture of selected traits. Nevertheless, so far the focus has been on the selective response triggered by a single stressor. Building on the highly parallel selection response of founder populations with reduced variation, we evaluated how the presence of a second stressor affects the genomic selection response. After 20 generations of adaptation to laboratory conditions at either 18°C or 29°C, strong genome-wide selection signatures were observed. Only 38% of the selection signatures can be attributed to laboratory adaptation (no difference between temperature regimes). The remaining selection responses are either caused by temperature-specific effe

SUBMITTER: Burny C 

PROVIDER: S-EPMC9579754 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature