Cardiac function unchanged following reanimation with normothermic regional perfusion in donation after circulatory death.

ABSTRACT:

Objectives

To determine whether hearts reanimated with normothermic regional perfusion (NRP) have clinically detectable changes in function using echocardiography comparing the prearrest and post-NRP imaging. As heart transplantation from donation after circulatory death (DCD) continues to increase, preliminary results suggest outcomes comparable with donation after brain death. It is unknown whether the obligatory period of warm ischemia experienced during DCD withdrawal process causes immediate changes in cardiac allograft function following in situ reanimation.

Methods

We retrospectively reviewed and compared predonation with postreanimation echocardiographic findings in all DCD donors at our institution from January to October 2021. All DCD donor organs were reanimated w

SUBMITTER: Markin NW 

PROVIDER: S-EPMC9579788 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature