Use of the Cancer and Aging Research Group Predictive Model for Chemotherapy-Related Toxic Effects in a Multiethnic, Older Adult Asian Population.

ABSTRACT:

Importance

The Cancer and Aging Research Group (CARG) prediction model for chemotherapy-related toxic effects has been developed but not yet validated in older Asian adults. In view of differences in drug metabolism and toxic effect reporting in the Asian population, the ability of this tool to guide the cancer treatment decision-making process in older Asian adults needs to be assessed.

Objective

To examine the validity of the CARG predictive model in a multiethnic Asian cohort of older adults.

Design, setting, and participants

In this prognostic study, patients of various Asian ethnicities 70 years or older with a solid tumor diagnosis receiving chemotherapy at the National University Cancer Institute, Singapore, were accrued from June 1, 2017, to January 1, 2019. T

SUBMITTER: Pang A 

PROVIDER: S-EPMC9579905 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature