Longitudinal associations between racial discrimination and hippocampal and white matter hyperintensity volumes among older Black adults.

ABSTRACT:

Rationale

Non-Hispanic Black older adults are at higher risk of Alzheimer's disease and related dementias (ADRD) than non-Hispanic Whites, which reflects racial disparities in both brain and cognitive health. Discrimination may contribute to these disparities, but much of the research on discrimination and ADRD outcomes is cross-sectional and/or does not disaggregate experiences of discrimination by attribution. Focusing specifically on racial discrimination and considering longitudinal brain outcomes may advance our understanding of the role of discrimination in explaining disproportionate rates of ADRD among non-Hispanic Black older adults.

Methods

In total, 221 non-Hispanic Black participants in the Washington Heights-Inwood Columbia Aging Project completed multiple measu

SUBMITTER: Zahodne LB 

PROVIDER: S-EPMC9579996 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature