Dataset Information

Effect of high-intensity interval training on aerobic capacity and fatigue among patients with prostate cancer: a meta-analysis.

ABSTRACT:

Objective

This study focused on evaluating whether high-intensity interval training (HIIT) had an effect on aerobic capacity and fatigue among patients with prostate cancer (PCa) and exploring its effect on the immune system of PCa patients.

Methods

To investigate the potential effect of HIIT on patients with prostate cancer, a meta-analysis was carried out. From January 2012 to August 2022, studies that met predefined criteria were searched in the Scopus, PubMed, Web of Science, and EBSCO databases. Analysis of the standardized mean differences was performed using Review Manager 5.4.1 software with a 95% confidence interval.

Results

This review examined a total of 6 articles. There were 215 male patients with PCa involved, and the mean age was 64.4 years. According to the results of the meta-analysis, the HIIT group (n = 63) had greater VO_2peak (P<0.01) than the control group (CON) (n = 52) (P = 0.30, I² = 19% in the heterogeneity test; MD, 1.39 [0.50, 2.27]). Moreover, fatigue was significantly different (P<0.01) between the HIIT (n = 62) and CON (n = 61) groups (P = 0.78, I² = 0% in the heterogeneity test; SMD, -0.52 [-0.88, -0.16]). Furthermore, among PCa patients, HIIT showed higher efficacy (P < 0.01) in decreasing PSA than the CON regimen (P=0.22, I² = 34% in the heterogeneity test; MD, -1.13 [-1.91, -0.34]).

Conclusions

HIIT improves aerobic capacity, fatigue, and PSA levels among PCa patients but does not significantly affect IL-6 or TNF-α content. Therefore, HIIT may be a novel and potent intervention scheme for PCa patients.

SUBMITTER: Chang M

PROVIDER: S-EPMC9580114 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature

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Publications

Effect of high-intensity interval training on aerobic capacity and fatigue among patients with prostate cancer: a meta-analysis.

Chang Ming M Wang Junguo J Hashim Hairul A HA Xie Shihao S Malik Adam A AA

World journal of surgical oncology 20221019 1

<h4>Objective</h4>This study focused on evaluating whether high-intensity interval training (HIIT) had an effect on aerobic capacity and fatigue among patients with prostate cancer (PCa) and exploring its effect on the immune system of PCa patients.<h4>Methods</h4>To investigate the potential effect of HIIT on patients with prostate cancer, a meta-analysis was carried out. From January 2012 to August 2022, studies that met predefined criteria were searched in the Scopus, PubMed, Web of Science, ...[more]

PMID: 36261844

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Project description:This study compared the acute physiological responses and performance changes during an integrated high-intensity interval aerobic and power protocol. Sixteen moderately trained athletes (age: 20.1 ± 2.2 years, body height: 180.0 ± 6.5 cm, body mass: 75.7 ± 6.4 kg, VO2max: 55.8 ± 4.3 mL/kg/min) performed a 2 × 6 min interval training protocol with 2 min passive recovery between sets on two different occasions in random and counterbalanced order. Each 6 min set included repeated periods of 15 s exercise interspersed with 15 s passive rest. On one occasion (RUN), all exercise periods included running at 100% of maximal aerobic speed, while on the other occasion an integrated protocol was used (INT) in which each of the two 6 min sets included 4 × 1.5 min periods of running exercise at 100% of maximal aerobic speed in combination with jumping (i.e., 2 × 15 running with 15 s rest and 1 × 15 s drop jumping with 15 s rest). Time spent above 85% HRmax was two-fold higher in INT compared to RUN (8.5 ± 3.6 vs. 4.3 ± 3.9 min, respectively, p = 0.0014). Interestingly, heart rate increased above 95% HRmax only in INT and almost no time was spent above 95% HRmax in RUN (1.4 ± 1.9 vs. 0.1 ± 0.2 min, respectively, p = 0.008). Blood lactate concentration at the end of the second set of INT was higher than RUN (7.3 ± 3.2 vs. 4.6 ± 2.7 mmol/L, p = 0.002). Countermovement jump was higher in INT after the end of second set by 6.4% (p = 0.04), 6.7% (p = 0.04), 7.8% (p < 0.01) and 7.3% (p < 0.001), at 2, 6 and 8 min after set 2. In conclusion, the comparison between INT and RUN shows that INT not only elicits higher physiological and metabolic responses, but also acutely enhances neuromuscular performance for at least 8 min after the end of exercise. The integrated running/jumping high-intensity interval exercise approach could be a very useful and time efficient method for strength and conditioning coaches, especially in team sports, in which the time available for the improvement of physical parameters is limited.

Dataset Information

Effect of high-intensity interval training on aerobic capacity and fatigue among patients with prostate cancer: a meta-analysis.

Objective

Methods

Results

Conclusions

Publications

Effect of high-intensity interval training on aerobic capacity and fatigue among patients with prostate cancer: a meta-analysis.

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