Recurrence pattern of non-syndromic familial congenital heart diseases among a large cohort of families from Egypt

ABSTRACT:

Background

Congenital heart diseases (CHD) are the commonest congenital anomalies with increased risk in children born from families with affected members. However, various recurrence patterns of CHDs have been reported in different populations. Therefore, this work aimed to assess the recurrence patterns of CHDs in a large sample of Egyptian families.

Methods

From January 2020 to October 2021, non-syndromic children with confirmed CHDs were recruited. Data were collected from guardians of the recruited children and hospital records, including the index case’s cardiac diagnosis and CHD diagnosis of other affected family members with to determine their recurrence pattern, consanguinity, and multi-gestation status.

Results

A total of 130 recurrent cases with CHD we

SUBMITTER: Rakha S 

PROVIDER: S-EPMC9580194 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature